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Of the 245 patients handled, 194 completed the examine; 70% reported Clinical International Impression of Improvement scale responses of “much improved” or “very a lot improved” between open-label baseline and ultimate visit (previous randomized modafinil group: 74%; placebo group: 66%). When information were analyzed for four subsets of patients (former modafinil responders, placebo responders, modafinil nonresponders, and placebo nonresponders), enhancements in scores on all outcome measures had been at the least twice as great among former modafinil and pla