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The median of Gram-positive infection-related antibiotic days was 10 days in the levofloxacin group versus 25 days in the ciprofloxacin group (p less then 0.0001). The median of Gram-negative infection-related antibiotics was 10 days in the levofloxacin group compared with 20 days in the ciprofloxacin group (p less then 0.0001). The number of days with body temperature ≥38 °C was significantly less in the levofloxacin group (p less then 0.001).Antibiotic resistance is occurring widely throughout the world and is affecting people of all