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How to Choose the Best ADHD Medication for Adults The most frequently prescribed medication by health professionals to treat ADHD is stimulants. They increase levels of dopamine and norepinephrine neurotransmitters in the brain to improve concentration and reduce the risk of impulsive behavior. They're available in immediate-release tablets or liquid and long-acting capsules (like Dynavel XR). Long-acting stimulants are less prone for abuse. are the first med