https://www.selleckchem.com/pr....oducts/nvp-tnks656.h
This suggests that insoluble aggregates of tau incorporate into the membrane and modify ionic currents, changing plasma membrane potential and activating VGCCs, which induces a calcium influx that triggers ROS production in NADPH oxidase. The combination of all these effects likely leads to toxicity, as only the same insoluble tau aggregates which demonstrated membrane-active properties produced neuronal cell death. This article is protected by copyright. All rights reserved.BACKGROUND Gallstone pancreatitis (GSP) has evidence-based
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