https://www.selleckchem.com/pr....oducts/Cryptotanshin
Mutations of the genes encoding aminoacyl-tRNA synthetases are highly associated with various central nervous system disorders. Recurrent mutations, including c.5AG, p.D2G; c.1367CT, p.S456L; c.1535GA, p.R512Q and c.1846_1847del, p. Y616Lfs*6 of RARS1 gene, which encodes two forms of human cytoplasmic arginyl-tRNA synthetase (hArgRS), are linked to Pelizaeus-Merzbacher-like disease (PMLD) with unclear pathogenesis. Among these mutations, c.5AG is the most extensively reported mutation, leading to a p.D2G mutatio
Like
Comment
Share
