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Contrasting the results of this study with those obtained in an earlier study of dry and fully hydrated collagen scaffolds, we were able to identify features that are important and peculiar to each material system. Highlighted in this study are newly determined robust structure-property-processing correlations as well as processing conditions and features that are critical for the mechanical performance of chitosan and other biopolymer scaffolds made by freeze casting for biomedical applications.Tissue engineering has recently gained p