https://www.selleckchem.com/pr....oducts/ly3039478.htm
Therefore, our results suggest that PAL may be a novel treatment strategy for ischemic stroke and cerebral I/R injury.Melatonin is a strong antioxidant which beneficially protects against middle cerebral artery occlusion (MCAO) followed by hemorrhagic transformation in rats; protection includes the reduction of neurological deficits, infarction, and hematoma volume. The molecular mechanisms underlying these neuroprotective effects in the MCAO model have not been clearly identified. This study examined the influence and involved mechan