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The in vivo experiments demonstrated that AE caused no obvious effects on the weight and pathological changes of mice. AE-mediated aPDT was effective in the treatment of MDR A. baumannii caused infections in mice after skin scald. AE has potential to be used in the photodynamic treatment of MDR A. baumannii caused superficial infections after scald. AE has potential to be used in the photodynamic treatment of MDR A. baumannii caused superficial infections after scald.Fourier Transform-Infrared (FT-IR) absorption spectroscopy has been use