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Schisandrin B is a bioactive substance with powerful antiinflammation and antioxidative properties, we thus speculated that Schisandrin B might act as a potential prospect for osteoporosis. In the present study, we unearthed that the formation and` purpose of osteoclasts were significantly stifled by Schisandrin B. And consistent with the in vitro outcomes, treatment with Schisandrin B attenuated ovariectomy-induced bone loss in mice. Moreover, Schisandrin B notabl