https://www.selleckchem.com/pr....oducts/Cyclopamine.h
The frequency of TIM-3+PD-1+NK cells in SLE patients with a cardiovascular disease (CVD) was significantly lower than that in SLE patients without a CVD. Moreover, the increased TIM-3+PD-1+ NK cells were significantly decreased in SLE patients following treatment. The present study suggested that the increased TIM-3+PD-1+ NK cells were associated with the disease activity and severity of SLE and may play a role in SLE pathogenesis. Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic condition of childhood. Genet