https://www.selleckchem.com/pr....oducts/2-2-2-tribrom
Furthermore, immunofluorescent staining of the lung tissue showed a GM-CSF+ neutrophil accumulation and a decreased citrullinated histone 3 expression after PLAG treatment. PLAG also downregulated the levels of IL-6 and TNF-α and upregulated the level of sIL-7Rα, an anti-fibrotic molecule. Our results indicate that PLAG might have a preventative effect on ILD development through the resolution of NETosis in the lung.Dupilumab is a fully humanized monoclonal antibody, capable of inhibiting intracellular signaling of both in
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