https://www.selleckchem.com/products/ABT-263.html
Canagliflozin is an anti-diabetic agent and sodium glucose co-transporter-2 inhibitor. Despite numerous clinical trials demonstrating its beneficial effects on blood pressure, the cellular mechanisms underlying the effects of canagliflozin on vascular reactivity have yet to be clarified. We investigated the vasodilatory effect of canagliflozin on aortic rings isolated from rabbits. We used rabbit thoracic aortic rings and its arterial tone was tested by using wire myography system. Canagliflozin caused concentration-dependent vasodilati
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