https://www.selleckchem.com/pr....oducts/dl-ap5-2-apv.
The in vitro activities of sulbactam/durlobactam and comparators were determined by broth microdilution. RESULTS The addition of durlobactam restored the activity of sulbactam against the majority of the strains tested. The MIC90 of sulbactam/durlobactam was 2 mg/L for all A. baumannii, compared with 64 mg/L for sulbactam alone. The MIC90 of sulbactam/durlobactam of 2 mg/L remained unchanged for 831 carbapenem-resistant isolates. Colistin was the only comparator with comparable activity (MIC90 = 1 mg/L). CONCLUSIONS This study demo