Causes of Truck Crash Accidents If a collision with a truck occurs, the driver may be at fault, but there are other factors that could contribute to an accident. The most frequent causes are fatigue of the driver or impaired driving, as well as the fact that a truck is loaded with hazardous cargo. The makers of these products could also be held responsible for any damages. If you have suffered injuries, you should seek medical attention as soon as possible. Keep a record of the crash and share information with the other party. Request a copy