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The differences between mean ADC values of malignant lesions and contralateral healthy tissues were significant for all the pairs of -value combinations. The pair of -values 50 and 1200 provided the highest AUC (0.94), with a sensitivity of 90.2%, a specificity of 92.6%, and an accuracy of 91.2% at an ADC cut-off of 1.23 × 10 mm /s. Our study showed that using a 1.5-Tesla MRI scanner the diagnostic performance of ADC values estimated from the -value pair 50 and 1200 s/mm was highest. However, some other -value pairs provided statically