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ADHD Medications - Stimulant Or Non Stimulant? Stimulant drugs are the most popular treatment for ADHD and for many people they work well. However, for some people individuals, they can cause adverse effects or don't help. Doctors sometimes prescribe non-stimulant ADHD medications instead, or in conjunction with stimulants. These medicines include ones that treat high blood pressure, for instance Clonidine and Guanfacine hcl (Tenex). They also include other medications that act to promote the state of being awake. Bene