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The Target-Decoy MineR is applicable to different types of quantitative data in tabular format. Supplementary data are available at Bioinformatics online. Supplementary data are available at Bioinformatics online. Patients with lower limb fractures who are non-weight bearing are at risk of the complications of the associated immobility and disability, particularly people with frailty, but there is lack of clarity about what constitutes optimal care for such patients. A scoping literature review was conducted to explore what evidence is