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ADHD Medications For Adults and Teenagers When a person's ADHD medication starts to work properly, they will notice that they are able to concentrate for longer durations. may also be more prone to falling asleep. Stimulants are among the most commonly used drugs prescribed for ADHD for adults. They can be immediate-release or long acting. Long-acting formulas can prevent "crash" effects that occur when stimulant medications wear off. Methylphenidate Methylphenidate stimulates the centra