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This should suggest the design of randomized controlled studies aimed at evaluating the effects of these drugs on testicular function. Fatty acids, specifically polyunsaturated fatty acids (PUFAs) play an important role in inflammation and its resolution, however, their interaction with the epigenome is relatively unexplored. Here we investigate the relationship between circulating blood fatty acids and the DNA methylation of the cytokine encoding gene tumour necrosis factor (TNF, OMIM 19116. Using a cross-sectional study approach, we
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