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Extensive experiments demonstrate that our method outperforms existing state-of-the-art load forecasting schemes in terms of the prediction accuracy and stability.A single blood vessel surrounded by the biological tissue with a tumor is considered. The influence of the heating technique (e.g. ultrasound, microwave, etc.) is described by setting a fixed temperature for the tumor which is higher than the blood and tissue temperature. The temperature distribution for the blood sub-domain is described by the energy equation written in the