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The aim of the study was to expand the understanding of pathogenesis of adenomyosis-associated pelvic pain. We studied 30 (n = 3 biopsy samples obtained after hysterectomy in women with diffuse adenomyosis of grade II-III, accompanied by severe pain syndrome, who did not receive hormonal therapy. The morphologic comparison group comprised 30 (n = 3 biopsy samples obtained from women with adenomyosis, without pain syndrome, operated on for abnormal uterine bleeding, who also did not receive hormone therapy. The total density of immu