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These combined properties make TOF-SIMS possibly a perfect technique to study oil-gas interfaces. TOF-SIMS spectra of three crude oils had been assessed, and only low-mass fragment ions could possibly be assigned to molecular structures unambiguously. Movies of crude oils had been incubated under atmosphere, oil vapor, or water vapor for assorted times. TOF-SIMS pictures of a polar crude oil revealed feeble structures of ∼10 μm large round patches that grew