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In the pets that obtained therapy, there was decrease in the lesion size and reduced amount of the parasitic load. Histopathological analysis of this remedies with GA, EA, and combinations with Amph B showed circumscribed lesions because of the existence of fibroblasts, granulation tissue, and collagen deposition, as well as the presence of activated macrophages. The formulations containing GA and EA triggered macrophages in every evaluated parameters, causing the activation of cells associate
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