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14% and 6.90% remained corrosion-suspected on used and new brackets, respectively. Used brackets showed more signs of corrosion than new ones. Combined assessment of SEM and EDS indicates that the bracket surface is affected during orthodontic treatment as a result of corrosion. Used brackets showed more signs of corrosion than new ones. Combined assessment of SEM and EDS indicates that the bracket surface is affected during orthodontic treatment as a result of corrosion. Optogenetic gene therapy to render remaining retinal cells light-s