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85; 95%CI, 0.78-0.92; P 0.001). There was high heterogeneity (I2 = 64.9%; P 0.001) among the studies. Subgroup analyses indicated that sample size and depression screening tools were the main sources of study heterogeneity. An inverse association between healthy dietary patterns and depression risk in older adults was found. However, the high heterogeneity among the studies should be considered. PROSPERO registration no. CRD 42020169195. PROSPERO registration no. CRD 42020169195. Obesity predisposes to multiple diseases, such