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This review provides an overview of available immunotherapeutic approaches used to treat GBMs. It discusses the limitations of conventional imaging and potential utilities of physiologic imaging techniques in the response assessment to immunotherapies. It also describes challenges associated with these imaging methods and potential solutions to avoid them.The magnesium alloys Mg-0.5Mn-2Zn, Mg-1.0Mn-2Zn, and Mg-1.5Mn-2Zn (wt.%) with potential biomedical applications, synthesized by powder metallurgy, were investigated to evaluate the inf