https://pdgfrsignaling.com/ocu....lar-pathology-and-so
Downregulation of TBK1 greatly suppressed RANKL-induced gene phrase of Mmp9, Atp6v0d2, Acp5, Ctsk andNfatc1 mixed up in regulation of OC formation and purpose both in BMM and RAW264.7 cells. Mechanistic studies indicated that TBK1 affected the NF-κB signaling path along with mitogen-activated necessary protein kinases (MAPKs) and necessary protein kinase B (Akt) activation during OC differentiation. Additionally, the protein level of TNF receptor-ass