https://www.selleckchem.com/pr....oducts/borussertib.h
Redox active metal cations, such as Cu2+, have been related to induce amyloid plaques formation and oxidative stress, which are two of the key events in the development of Alzheimer's disease (AD) and others metal promoted neurodegenerative diseases. In these oxidative events, standard reduction potential (SRP) is an important property especially relevant in the reactive oxygen species formation. The SRP is not usually considered for the selection of drug candidates in anti-AD treatments. In this work, we present a computational pro