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miR-31 levels had been altered by cellular transfection and detected by RT-qPCR. Also, the related-proteins of paths were additionally detected by western blot. RESULTS Anti-miR-31 increased DAOY and UW228 cells viability, BrdU+ figures, and phrase of CyclinD1. The migration/invasion price and expression quantities of MMP-9 and vimentin after anti-miR-31 transfection had been increased. Moreover, anti-miR-31 enhanced cells' cisplatin resistance and t