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4-Methylcyclohexane methanol (MCHM) is a hydrotrope that causes growth arrest in fungus. We discovered that a naturally occurring variation within the Med15 allele, an element associated with Mediator end, modified the stress reaction to numerous chemicals in addition to MCHM. Med15 contains two polyglutamine repeats (polyQ) of adjustable lengths that modification the gene appearance of diverse paths. The Med15 necessary protein existed in multiple isoforms as well as its security was dep