https://sphksignal.com/index.p....hp/long-term-pain-ki
Morphine visibility increased the dopaminergic markers (D1R, D3R, DAT) and ΔFosB immunoreactivity when you look at the ventral striatum; nevertheless, FA-Nc treatment decreased D1R, D3R, and ΔFosB and increased D2R, DAT, and NRF2. In conclusion, FA-Nc treatment prevented the morphine reinstatement, promoted anti-oxidant task, and modified the dopaminergic neurotransmission, NRF2, and ΔFosB, what may indicate a neuroprotective and antioxidant part of the nanoformulation.We used a vari