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Treating ADHD Without Medication Many people suffering from ADHD are able to manage their symptoms without medication. Combining psychotherapy, behavior change and natural remedies is often the best solution. Certain medications like methylphenidate boost brain chemicals that regulate attention and impulses. Nonstimulants, like guanfacine and atomoxetine are available as well. Psychotherapy, exercise and good sleep habits can also be beneficial. Some patients with ADHD also have coexisting condi