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METHOD We systematically searched and identified appropriate researches published before July 2019 from PubMed and Embase. Six scientific studies concerning 162 individuals had been included into our last evaluation. RESULT The data showed that the effective price of MVD ended up being 70.1% (95% CI 0.602-0.801). The most common offending vessel had been PICA (29.9%), followed closely by VA/BA (23.9%) and VA/BA plus PICA (12.7%). Problems had been mostly related to the VII, VIII,