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3D bioprinting is the increasing technique for the fabrication of large structure constructs which offers a potential answer for unmet clinical requirements in breast reconstruction building on decades of expertise in autologous fat grafting, adipose-derived mesenchymal stem cell (ASC) biology and TE. A scaffold was bioprinted using encapsulated ASC spheroids in methacrylated gelatin ink (GelMA). Uniform ASC spheroids with a great geometry and diameter for bioprinting had