https://www.selleckchem.com/mTOR.html
A study published in Cancer Research in 2004 by Rodriguez and colleagues identified the existence of arginase-producing myeloid cells in tumors distinct from macrophages. They demonstrated the role of arginase in negative regulation of T-cell function in vivo This was one of the first reports implicating cells, which later were named myeloid-derived suppressor cells (MDSC), in T-cell suppression in vivo and linking this effect with arginase activity and expression. This work was important in advancing the field of MDSC research and helped to bring
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