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How to Choose the Best ADHD Medication for Adults Stimulant medications like methylphenidate and amphetamine are effective in boosting and balancing levels of brain chemicals. Doctors prescribe them as pills, liquids or patches. ADHD can be treated by health professionals using drugs called alpha-2 agonists as well as norepinephrine reup inhibitors. These are usually used "off-label" for this purpose as they're FDA-approved to treat other conditions. Stimulants The stimulants are the most commonly used ADHD medication prescribed. They boost levels of the brain ch