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How Does ADHD Medication Work? Many people discover that ADHD medication helps them concentrate, focus and control their impulsive behaviour. It can be a long process to determine the appropriate medication and dose for each person. Some children's sleep patterns can be affected by medication. If they are sleeping better, it is a sign that the medication is working. 1. Stimulants Stimulants are the most popular prescription drugs that doctors employ to treat ADHD. They increase the levels of certain chemicals (neurotransmitters) in your brain, which