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8% (Death group), 37% (Hospital Discharge group), 16.1% (Convalescent Plasma group) and 16.2% (Control group) ( =0.027). The self-declared race ( 0.001) and the occurrence of in hospital death ( =0.058) were independently associated with the presence of the allele. Hypertension ( 0.001), age ( 0.001) and the presence of at least one allele ( =0.009) were independently associated with the need for hospitalization. There is a suggestive association between the presence of the and the severity of COVID-19. This may be a mechanism underlying the