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Pooled results demonstrated that breast cancer as the primary tumor location (HR = 2.73, 95% CI 2.12-3.52) and multiple BMs (HR = 1.37, 95% CI 1.18-1.58) were significantly associated with a higher risk of LMD occurrence. Breast cancer origin and multiple BMs increase the risk of LMD occurrence after neurosurgery. Several other risk factors which might play a role in LMD development were also identified. Breast cancer origin and multiple BMs increase the risk of LMD occurrence after neurosurgery. Several other risk factors which might p
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