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PURPOSE We examined the capacity for the pan-fibroblast growth element receptor (FGFR) inhibitor AZD4547 to increase radiation response across a panel of head and throat squamous mobile carcinoma (HNSCC) cellular lines and xenografts. EXPERIMENTAL DESIGN FGFR1, FGFR2, FGFR3 RNA in situ hybridization (ISH) phrase was assessed in a cohort of HNSCC patient samples, cell outlines and patient-derived xenografts (PDXs). In vitro ramifications of