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How to Choose the Best ADHD Medication for Adults Stimulant medications like methylphenidate and amphetamine are effective in boosting and balancing brain chemicals. Doctors prescribe them as pills, liquids or patches. ADHD can be treated by health professionals using drugs known as alpha-2 agonists and norepinephrine-reuptake inhibitors. These medications are typically used "off-label", since they are FDA-approved for different conditions. Stimulants The stimulants are