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The binding internet sites between ANRIL and let-7b-5p had been predicted by StarBase v.3.0 and confirmed using dual-luciferase reporter assay. Outcomes Sevoflurane treatment repressed proliferation and migration of glioma cells. The appearance of ANRIL had been downregulated in glioma cells after therapy with sevoflurane in a dose-dependent manner, and overexpression of ANRIL reversed sevoflurane-induced inhibition of proliferation and migration of glioma cells. Furthermore, let-7b-5p