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OBJECTIVE To examine the prevalence and risk factors of oral mucositis in children with acute lymphoblastic leukemia in Dr. Soetomo Hospital Surabaya, Indonesia. METHODS This study was a case-control study with frequency distribution design, describes the incidence of oral mucositis in children suffering from acute lymphoblastic leukemia who underwent chemotherapy in RSUD Dr. Soetomo. The sampling technique used was consecutive non-random sampling. In this study, the incidence of mucositis was not differentiated based on the type of chemotherapy received by