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A rapid, sensitive method for assaying volatile impact compounds in white wine was developed using gas chromatography-tandem mass spectrometry (GC-MS/MS) technology, with a triple quadrupole analyzer operating in chemical ionization and electron impact mode. This GC-MS/MS method made it possible to assay volatile thiols (3SH 3-sulfanylhexanol, formerly 3MH; 3SHA 3-sulfanylhexyl acetate, formerly 3MHA; 4MSP 4-methyl-4-sulfanylpentan-2-one, formerly 4MMP; BM benzenemethanethiol; E2SA ethyl 2-sulfanylacetate; and 2FM 2-furanmethanethiol) a