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ADHD Medication - Stimulants Stimulants alter how the brain releases chemicals which can affect concentration. Doctors usually start patients with ADHD with stimulants and gradually increase the dose that aids them. Antidepressants are also used by people suffering from ADHD (not only for depression). These drugs work using the same chemical as stimulants but have less negative side consequences. Stimulants The first medication that doctors prescribe for ADHD is stimulants. They i