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In this analysis, we discuss how the LGLL mutational structure allows a more exact and detailed tumor stratification, recommending new variables for better management of the illness and hopefully paving the way in which for a targeted clinical approach. Copyright © 2020 Teramo, Barilà, Calabretto, Vicenzetto, Gasparini, Semenzato and Zambello.Objective Recently, performing locoregional surgical treatment nevertheless stays debatable in clients with metastatic breast cancer (MBC). Present st