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Pooled estimates included odds ratios of 1.48 (95%CI 0.75-2.93) favoring female sex, 1.26 (95%CI 0.68-2.36) favoring Caucasian race, and a mean difference in AHI of 4.32 (95%CI -0.61-9.26) events/hour between adherent and non-adherent groups. There was low quality evidence to suggest that psychosocial factors like health cognitions and family environment may predict adherence. CONCLUSION In this novel systematic review, we identified several factors associated with increased odds of PAP therapy adherence in children. These findings may