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001). No statistical difference was found through the clinical location assessment ( = 0.756), as well as the cartilage imaging assessment ( = 0.756). The mean MOCART 2.0 scale was 67.67 (range 50-85). Treating full-thickness patellofemoral osteochondral lesions with microfractures associated with a chitosan scaffold proved to be effective regarding defect filling and symptomatic improvement. Treating full-thickness patellofemoral osteochondral lesions with microfractures associated with a chitosan scaffold proved to be effective regard