https://cathepsink.com/types-s....plendour-strategy-by
In this report, a novel signal-on electrochemical biosensor on the basis of the usage of electrochemically controlled grafting of polymers as an amplification strategy is described for the ultrasensitive assay of trypsin activity. The carboxyl-group-free peptide, offering once the substrate when it comes to recognition of trypsin, is very first immobilized via its N-terminus. The tryptic cleavage of peptide substrate can generate a free carboxyl group during the C-terminus of this truncated peptide, to which through the carboxyl