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In this Review, we provide an overview of this development, framework, and purpose of lymphatic vessels within the healthier adult renal. We then highlight the contributions of lymphatic vessels to multiple types of renal pathology, emphasizing CKD, transplant rejection, and polycystic kidney illness and discuss strategies to focus on renal lymphatics making use of genetic and pharmacologic methods. Overall, we argue the case for lymphatics playing a simple role in renal physiology and pa